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Chemical Structure : YTH domain inhibitor N-7
Catalog No.: PC-22985Not For Human Use, Lab Use Only.
YTH domain inhibitor N-7 is a specific small molecule, pan-inhibitor of YTH domain-containing m6A RNA readers with IC50 of 30-48 uM for human YTHDF1, YTHDF2, YTHDF3, YTHDC1, and YTHDC2 proteins.
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YTH domain inhibitor N-7 is a specific small molecule, pan-inhibitor of YTH domain-containing m6A RNA readers with IC50 of 30-48 uM for human YTHDF1, YTHDF2, YTHDF3, YTHDC1, and YTHDC2 proteins.
N-7 shows selective binding to YTH domain proteins over non-YTH m6A recognition protein FTO.
| M.Wt | 372.43 | |
| Formula | C18H24N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang CH, et al. RSC Chem Biol. 2024 Jul 25;5(9):914-923.
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