YU-101 | Proteasome β5 inhibitor | Probechem Biochemicals

Chemical Structure : YU-101

YU-101 (YU101, YU 101)

Catalog No.: PC-60971Not For Human Use, Lab Use Only.

YU-101 is a potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.

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Biological Activity

YU-101 is a potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.

Physicochemical Properties

M.Wt	634.818
Formula	C36H50N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((S)-2-acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

References

1. Screen M, et al. J Biol Chem. 2010 Dec 17;285(51):40125-34.

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YU-101 (YU101, YU 101)

Biological Activity

Physicochemical Properties

References

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