YX84

Chemical Structure : YX84

Catalog No.: PC-26582Not For Human Use, Lab Use Only.

YX84 is a slow-onset, potent positive allosteric modulator (PAM) of GABA A receptor with EC50 of 0.9 uM.

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Biological Activity

YX84 is a slow-onset, potent positive allosteric modulator (PAM) of GABA A receptor with EC50 of 0.9 uM.

M.Wt	540.64
Formula	C28H35F3O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,10R,13S,17S)-10,13-dimethyl-17-((4-(2,2,2-trifluoroacetyl)benzyl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3-sulfonic acid

1. Shu HJ, et al. bioRxiv [Preprint]. 2026 Apr 8:2026.04.06.716659.