Z-DON |CAS:1026102-99-7 Probechem Biochemicals

Chemical Structure : Z-DON

Catalog No.: PC-61055Not For Human Use, Lab Use Only.

Z-DON (Z-ZON-Val-Pro-Leu-OMe) is a potent, irreversible and cell permeable inhibitor of tissue transglutaminase with IC50 of 20 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Z-DON (Z-ZON-Val-Pro-Leu-OMe) is a potent, irreversible and cell permeable inhibitor of tissue transglutaminase with IC50 of 20 nM.

M.Wt	628.727
Formula	C31H44N6O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzyloxycarbonyl-(6-Diazo-5-oxonorleucinyl)-L-Valinyl-L-Prolinyl-L-Leucinmethyl ester

1. Almami I, et al. Br J Pharmacol. 2014 Aug;171(16):3946-60.

2. Algarni AS, et al. Eur J Pharmacol. 2018 Feb 5;820:113-129.

3. Vyas FS, et al. Eur J Pharmacol. 2018 Jan 15;819:144-160.