| Cat. No. |
Product Name |
Information |
| PC-42933 |
CB-839
Glutaminase-1 (GLS1) inhibitor
|
CB-839 (Telaglenastat) is a potent, selective, and orally bioavailable inhibitor of glutaminase with IC50 of 28 and 23 nM for glutaminase-1 (GLS1) in kidney and brain (GAC and KGA), but not the liver form of glutaminase (GLS2, IC50>1 uM). |
| PC-21656 |
ERW1041E
TG2 inhibitor
|
ERW1041E is a specific, irreversible small molecule transglutaminase 2 (TGase 2; TG2) inhibitor with Ki of 11 uM. |
| PC-21655 |
MD102
TG2 inhibitor
|
MD102 is a potent transglutaminase 2 (TGase 2; TG2) inhibitor with IC50 of 0.35 uM, shows p53 stabilization effect and anticancer activity at RCC cell lines. |
| PC-38770 |
ZED1227
TG2 inhibitor
|
ZED1227 is a potent, selective, covalent, and orally active transglutaminase 2 (TGase 2, TG2) inhibitor with IC50 of 45 nM. |
| PC-35734 |
TTGM 5826
TGase inhibitor
|
TTGM 5826 (TTGM5826, TTGM-5826) is a small molecule, potential modulator of tissue transglutaminase (tTG) conformation. |
| PC-35603 |
JHU-083
Glutaminase inhibitor
|
JHU-083 is an orally available prodrug of the glutaminase inhibitor 6-diazo-5-oxo-L-norleucine (DON), blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.. |
| PC-35093 |
UPGL00004
Glutaminase inhibitor
|
UPGL00004 (UPGL 00004) is a potent, allosteric inhibitor of glutaminase C (GAC) with IC50 of 29 nM. |
| PC-43147 |
BPTES
GLS1 inhibitor
|
BPTES is a potent, selective kidney-type glutaminase 1 (GLS1) inhibitor with Ki of 3 uM (rat KGA), selective for GLS1 over GLS2, glutamate dehydrogenase, and γ-glutamyl transpeptidase. |
| PC-43146 |
Glutaminase C inhibitor 968
Gutaminase C inhibitor
|
Glutaminase C inhibitor 968 is a small molecule allosteric inhibitor of glutaminase C (GAC) catalytic activity with Kd of 3 uM, specifically inhibited the growth of transformed cells and various cancer cells by blocking GAC activation. |
| PC-42986 |
GK921
TG2 inhibitor
|
GK921 is a specific, orally active Transglutaminase 2 (TGase 2, TG2) inhibitor with IC50 of 7.71 uM against recombinant hTGase 2. |
| PC-61055 |
Z-DON
Tissue transglutaminase inhibitor
|
Z-DON (Z-ZON-Val-Pro-Leu-OMe) is a potent, irreversible and cell permeable inhibitor of tissue transglutaminase with IC50 of 20 nM. |
| PC-61053 |
L 682777
hTG2 inhibitor
|
L 682777 is a potent, irreversible inhibitor of human tissue transglutaminase (hTG2). |
