Z247611722 | Serine palmitoyltransferase inhibitor, Antifungal

Chemical Structure : Z247611722

Z247611722 (Z-247611722)

Catalog No.: PC-28604Not For Human Use, Lab Use Only.

Z247611722 is a novel antifungal, inhibitor of sphingolipid biosynthesis and serine palmitoyltransferase (SPT) displays fungicidal activity against multiple Candida species (C. albicans, MIC=1.56 uM) and fluconazole-resistant isolates.

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Biological Activity

Physicochemical Properties

M.Wt	345.29
Formula	C16H12FN3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1,3-dimethyl-2,4,7-trioxo-1,3,4,7-tetrahydro-2H-pyrano[2,3-d]pyrimidin-6-yl)-4-fluorobenzamide

References

1. Nysten J, et al. Nat Commun. 2026 Sep 15;17(1):10813.

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Z247611722 (Z-247611722)

Biological Activity

Physicochemical Properties

References

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