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ZAP-70 inhibitor 20

Chemical Structure : ZAP-70 inhibitor 20

CAS No.: 207284-01-3

ZAP-70 inhibitor 20

Catalog No.: PC-21066Not For Human Use, Lab Use Only.

ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk.

Physicochemical Properties

M.Wt 450.54
Formula C24H30N6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

COC1=C(OC)C(OC)=CC(NC2=NC=CC(C3=CC=C(N4C[C@H](CC)NCC4)N=C3)=N2)=C1

References

1. D Moffat, et al. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3351-6.

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