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Chemical Structure : ZAP-70 inhibitor 26
Catalog No.: PC-21065Not For Human Use, Lab Use Only.
ZAP-70 inhibitor 26 is a potent, highly selective ZAP-70 kinase inhibitor with IC50 of 88 nM, shows high selectivity over structurally related Syk (IC50>10 uM).
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ZAP-70 inhibitor 26 is a potent, highly selective ZAP-70 kinase inhibitor with IC50 of 88 nM, shows high selectivity over structurally related Syk (IC50>10 uM).
ZAP-70 inhibitor 26 also shows no activity against a panel of kinases, including Lck, PKCβ2, EGFR, Src, ERK-1, JNK 1, and p38α (IC50>10 uM).
| M.Wt | 516.56 | |
| Formula | C27H28N6O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Akihito Hirabayashi, et al. Bioorg Med Chem. 2009 Jan 1;17(1):284-94.
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