ZM-306416 | VEGFR inhibitor | Probechem Biochemicals

Chemical Structure : ZM-306416

CAS No.: 690206-97-4

ZM-306416 (ZM306416, CB 676475)

Catalog No.: PC-23466Not For Human Use, Lab Use Only.

ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50 of 0.1 μM and 2 μM for KDR and Flt, respectively, also inhibits EGFR with IC50 of <10 nM.

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10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$198	In stock
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Biological Activity

ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50 of 0.1 μM and 2 μM for KDR and Flt, respectively, also inhibits EGFR with IC50 of <10 nM.

Physicochemical Properties

M.Wt	333.75
Formula	C16H13ClFN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine

References

1. Han SY, et a. Bioorg Med Chem Lett. 2006 Jan 1;16(1):129-33.

2. Antczak C, et al. J Biomol Screen. 2012 Aug;17(7):885-99.

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ZM-306416 (ZM306416, CB 676475)

Biological Activity

Physicochemical Properties

References

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