Chemical Structure : ZM-306416
CAS No.: 690206-97-4
Catalog No.: PC-23466Not For Human Use, Lab Use Only.
ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50 of 0.1 μM and 2 μM for KDR and Flt, respectively, also inhibits EGFR with IC50 of <10 nM.
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ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50 of 0.1 μM and 2 μM for KDR and Flt, respectively, also inhibits EGFR with IC50 of <10 nM.
M.Wt | 333.75 | |
Formula | C16H13ClFN3O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine |
1. Han SY, et a. Bioorg Med Chem Lett. 2006 Jan 1;16(1):129-33.
2. Antczak C, et al. J Biomol Screen. 2012 Aug;17(7):885-99.
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