ZNL-05-044 | CDK11 inhibitor | Probechem Biochemicals

Chemical Structure : ZNL-05-044

CAS No.: 3034411-38-3

ZNL-05-044 (CDK11 inhibitor)

Catalog No.: PC-38750Not For Human Use, Lab Use Only.

ZNL-05-044 is a potent, selective CDK11 inhibitor with Kd of 69 nM (CDK11A), shows significantly kinome-wide selectivity.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

ZNL-05-044 is a potent, selective CDK11 inhibitor with Kd of 69 nM (CDK11A), shows significantly kinome-wide selectivity.
ZNL-05-044 treatment leads to G2/M cell cycle arrest, impacts CDK11-dependent mRNA splicing in cells.

Physicochemical Properties

M.Wt	477.408
Formula	C21H22Cl2N6OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-amino-2-((2-methyl-6-(4-methylpiperazin-1-yl)pyridin-3-yl)amino)thiazol-5-yl)(2,6-dichlorophenyl)methanone

References

1. Li Z, et al. Eur J Med Chem. 2022 May 8;238:114433.

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