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Chemical Structure : Zerumbone
CAS No.: 471-05-6
Catalog No.: PC-22863Not For Human Use, Lab Use Only.
Zerumbone is a natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet with anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity, binds to transgelin (TAGLN) and reduces the retention of USP1 in the cytoplasm and the degradation of ZEB1 ubiquitination.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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Zerumbone is a natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet with anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity, binds to transgelin (TAGLN) and reduces the retention of USP1 in the cytoplasm and the degradation of ZEB1 ubiquitination.
Zerumbone inhibits proliferation of a wide variety of tumor cells, on the activity of Hsp90.
Zerumbone enhanced the ATPase activity of cyanobacterial Hsp90 (Hsp90SE), yeast Hsp90, and human Hsp90α.
Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha.
| M.Wt | 218.34 | |
| Formula | C15H22O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trienone |
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1. Yinan Li, et al. Cell Biosci. 2023 May 6;13(1):80.
2. Nakamoto H, et al. Biochem J. 2018 Aug 16;475(15):2559-2576.
3. Singh SP, et al. Sci Rep. 2018 Mar 6;8(1):4090.
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