Chemical Structure : Ziftomenib
CAS No.: 2134675-36-6
Catalog No.: PC-72438Not For Human Use, Lab Use Only.
Ziftomenib (KO-539) is a potent, highly selective, oral menin inhibitor, demonstrates encouraging clinical activity as monotherapy for relapsed/refractory NPM1-mutated (NPM1-m) and KMT2A-rearranged AML.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
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| 100 mg | Get quote |
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Ziftomenib (KO-539) is a potent, highly selective, oral menin inhibitor, demonstrates encouraging clinical activity as monotherapy for relapsed/refractory NPM1-mutated (NPM1-m) and KMT2A-rearranged AML.
| M.Wt | 717.875 | |
| Formula | C33H42F3N9O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1H-Indole-2-carbonitrile, 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1-[(2S)-2-[4-(methylsulfonyl)-1-piperazinyl]propyl]- |
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1. Cancer Discov. 2021 Feb;11(2):216-217.

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