Chemical Structure : Zopolrestat
CAS No.:
110703-94-1
Zopolrestat
(CP73850, CP-73850)
Catalog No. : PC-25938Not For Human Use, Lab Use Only.
Zopolrestat (CP73850) is Zopolrestat (CP73850) is a potent, orally active aldose reductase (AR) inhibitor with IC50 of 3.1 nM (human placenta AR).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2593801
Biological Activity
Zopolrestat (CP73850) is Zopolrestat (CP73850) is a potent, orally active aldose reductase (AR) inhibitor with IC50 of 3.1 nM (human placenta AR).
Physicochemical Properties
M.Wt
419.38
Formula
C19H12F3N3O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(4-Oxo-3-((5-(trifluoromethyl)benzo[d]thiazol-2-yl)methyl)-3,4-dihydrophthalazin-1-yl)acetic acid
References
1. Mylari BL, et al. J Med Chem. 1991 Jan;34(1):108-22.
2. Inskeep PB, et al. Pharm Res. 1991 Dec;8(12):1511-5.
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