dCeMM2

Chemical Structure : dCeMM2

CAS No.: 296771-07-8

Catalog No.: PC-21962Not For Human Use, Lab Use Only.

dCeMM2 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
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Biological Activity

dCeMM2 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.

Physicochemical Properties

M.Wt	370.82
Formula	C16H11ClN6OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(5-chloropyridin-2-yl)acetamide

References

1. Mayor-Ruiz C, et al. Nat Chem Biol. 2020;16(11):1199-1207.

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dCeMM2

Biological Activity

Physicochemical Properties

References

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