dPTBD

Chemical Structure : dPTBD

Catalog No.: PC-27582Not For Human Use, Lab Use Only.

dPTBD is a copper ionophore and cuproptosis inducer, promotes intracellular copper accumulation particularly in the mitochondria, leading to metabolic disruption and cuproptotic cell death, exhibits significant antitumor efficacy in KRAS-driven cancers both in vitro and in vivo.

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Biological Activity

Physicochemical Properties

M.Wt	296.39
Formula	C16H16N4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N1,N1-dimethyl-N4-(4-(pyridin-2-yl)thiazol-2-yl)benzene-1,4-diamine

References

1. Sun Y, et al. Cancer Lett. 2026 Aug 3:218773.

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dPTBD

Biological Activity

Physicochemical Properties

References

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