Catalog No.: PC-72297Not For Human Use, Lab Use Only.
iBAP (BAP1 inhibitor I, BAP1-IN-1) is a first-in-class inhibitor of the catalytic activity of BRCA1 associated protein 1 (BAP1) histone H2A deubiquitinase complex with IC50 of 0.5-1 uM in vitro, inhibits truncated-ASXL1-driven leukemic gene expression and impairs tumor progression in vivo.
iBAP (BAP1 inhibitor I, BAP1-IN-1) is a first-in-class inhibitor of the catalytic activity of BRCA1 associated protein 1 (BAP1) histone H2A deubiquitinase complex with IC50 of 0.5-1 uM in vitro, inhibits truncated-ASXL1-driven leukemic gene expression and impairs tumor progression in vivo.
