Chemical Structure : iGOT1-01
CAS No.: 882256-55-5
Catalog No.: PC-35823Not For Human Use, Lab Use Only.
iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.
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iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.
Inhibition of GOT1 preferentially leads to accumulation of the M+4 aspartate isotopologue from 13C-glutamine in pancreatic cancer cells
M.Wt | 320.396 | |
Formula | C19H20N4O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(1H-indol-4-yl)-N-phenylpiperazine-1-carboxamide |
1. Holt MC, et al. Biochemistry. 2018 Nov 12. doi: 10.1021/acs.biochem.8b00914.
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