iGOT1-01 |CAS:882256-55-5 Probechem Biochemicals

Chemical Structure : iGOT1-01

CAS No.: 882256-55-5

iGOT1-01

Catalog No.: PC-35823Not For Human Use, Lab Use Only.

iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.

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10 mg	$158	In stock
25 mg	$278	In stock
50 mg	$498	In stock
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Biological Activity

iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.
Inhibition of GOT1 preferentially leads to accumulation of the M+4 aspartate isotopologue from 13C-glutamine in pancreatic cancer cells

Physicochemical Properties

M.Wt	320.396
Formula	C19H20N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1H-indol-4-yl)-N-phenylpiperazine-1-carboxamide

References

1. Holt MC, et al. Biochemistry. 2018 Nov 12. doi: 10.1021/acs.biochem.8b00914.

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iGOT1-01

Biological Activity

Physicochemical Properties

References

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