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Chemical Structure : mTOR-IN-1
CAS No.: 1207358-59-5
Catalog No.: PC-45461Not For Human Use, Lab Use Only.
A potent and selective mTOR inhibitor with Ki of 1.5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $268.8 | In stock | |
| 50 mg | $724.8 | In stock |
Bulk size, bulk discount!
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A potent and selective mTOR inhibitor with Ki of 1.5 nM; >500-fold selectivity over closely related PI3 kinases; exhibits suitable mouse PK and demenstrates active in an NCI-PC3prostate cancer model; orally bioavailable.
| M.Wt | 474.5581 | |
| Formula | C25H30N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(2-pyrimidinyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]- |
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1. Koehler MF, et al. J Med Chem. 2012 Dec 27;55(24):10958-71.
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