trans-VUF25471 | ACKR3 agonist | Probechem Biochemicals

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Chemical Structure : trans-VUF25471

trans-VUF25471 (ACKR3 agonist trans-3e)

Catalog No.: PC-24281Not For Human Use, Lab Use Only.

trans-VUF25471 is a small moleculephotoswitchable atypical chemokine receptor 3 (ACKR3) agonist, can be effectively switched from its thermodynamically stable trans state to the less active cis-isomer with a photostationary state of 96%.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	396.51
Formula	C23H29FN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	trans-N-(tert-butyl)-1-(3-((4-fluorophenyl)diazenyl)benzyl)piperidine-4-carboxamide

References

1. Sophie Bérenger, et al. ACS Omega. 2025 Feb 18;10(8):8675-8686.

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trans-VUF25471 (ACKR3 agonist trans-3e)

Biological Activity

Physicochemical Properties

References

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