Catalog No.: PC-25556Not For Human Use, Lab Use Only.
α-difluoromethylornithine (DFMO, Eflornithine, MDL71782) is a specific, irreversible inhibitor of polyamine biosynthesis enzyme Ornithine decarboxylase (ODC) with biochemicals IC50 of 252 uM, binding competitively with ornithine.
α-difluoromethylornithine (DFMO, Eflornithine, MDL71782) is a specific, irreversible inhibitor of polyamine biosynthesis enzyme Ornithine decarboxylase (ODC) with biochemicals IC50 of 252 uM, binding competitively with ornithine.
Physicochemical Properties
M.Wt
182.17
Formula
C6H12F2N2O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2,5-Diamino-2-(difluoromethyl)pentanoic acid
References
1. Schultz CR, et al. J Med Chem. 2025 Mar 13;68(5):5760-5773.
2. Lipke DW, et al. Clin Exp Hypertens. 1997 Apr;19(3):297-312.
