Chemical Structure : δ-secretase inhibitor 11a
CAS No.:
2565572-83-8
δ-secretase inhibitor 11a
(AEP inhibitor CP#11A, AEP-IN-2)
Catalog No. : PC-28350Not For Human Use, Lab Use Only.
δ-secretase inhibitor 11a (AEP inhibitor CP#11A) is a potent, selective δ-secretase (Asparagine endopeptidase, AEP, Legumain) inhibitor with IC50 of 10 nM, and binding affinity Kd of 5.5 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2835001
Biological Activity
δ-secretase inhibitor 11a (AEP inhibitor CP#11A) is a potent, selective δ-secretase (Asparagine endopeptidase, AEP , Legumain) inhibitor with IC50 of 10 nM, and binding affinity Kd of 5.5 nM.
Physicochemical Properties
M.Wt
363.40
Formula
C14H17N7O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(7-((5-(methylamino)-1,3,4-thiadiazol-2-yl)amino)-4-morpholinobenzo[c][1,2,5]oxadiazol-5-yl)methanol
References
1. Jianming Liao, et al. Neuropharmacology.
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