| Cat. No. |
Product Name |
Information |
| PC-24810 |
HEAL-116
3βHSD1 inhibitor
|
HEAL-116 is a potent, selective 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor, shows binding specificity to the substrate-binding pocket of 3βHSD1 and effectively neutralizes the local charge environment. |
| PC-24097 |
Emodin
11β-HSD1 inhibitor, Nrf2 activator
|
Emodin (Frangula emodin) is an anthraquinone derivative with anti-SARS-CoV activity, blocks the SARS coronavirus spike protein and ACE2 interaction, also inhibits casein kinase-2 (CK2), also activates Nrf2 and effectively targets PD pathology. |
| PC-20841 |
AMG221
11beta-HSD1 inhibitor
|
AMG221 is a potent, selective orally active 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor with Ki of 12.8 nM and cell IC50 of 10.1 nM. |