| PC-25718 |
SSR240612
B1R antagonist
|
SSR240612 is a potent, selective, non-peptide antagonist of bradykinin (BK) B(1) receptor, inhibits binding of [(3)H]Lys(0)-des-Arg(9)-BK to B(1) receptor in human fibroblast MRC5 and to recombinant human B(1) receptor expressed in human embryonic kidney cells with Ki of 0.48 and 0.73 nM, respectively. |