| Cat. No. |
Product Name |
Information |
| PC-60178 |
TAK-243
UAE1 inhibitor
|
TAK-243 (MLN7243, AOB87172) is a small-molecule, cell-permeable inhibitor of ubiquitin-activating enzyme E1 (UAE1) with IC50 of 1 nM. |
| PC-27370 |
SC023
SERCA2a SUMOylation activator
|
SC023 is a second-generation N106 analog and small-molecule enhancer of SERCA2a SUMOylation, targets the SUMO E1 enzyme to trigger intrinsic SERCA2a SUMOylation without altering SUMO-related regulatory enzymes. |
| PC-24868 |
UBA5 inhibitor Compound 8.5
UBA5 inhibitor
|
UBA5 inhibitor Compound 8.5 (UBA5-IN-1) is a potent, selective UFM1 activating E1 enzyme UBA5 inhibitor with IC50 of 4.0 uM (inhibition of UFM1 transthiolation from UBA5 to UFC1). |