Chemical Structure : (R)-(-)-Ibuprofen
CAS No.:
51146-57-7
(R)-(-)-Ibuprofen
((R)-Ibuprofen)
Catalog No.: PC-45990Not For Human Use, Lab Use Only.
An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids; inhibits NF-κB activation (IC50=121.8 uM) in response to T-cell stimulation as well as block superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 =40-100 uM).
Pain
Approved
Physicochemical Properties
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M.Wt
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206.2808
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Formula
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C13H18O2
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20 °C 12 Months; 4°C 6 Months
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- In Solvent
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-80 °C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αR)-
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References
1. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
2. Evans AM. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.
3. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
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