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Chemical Structure : (R)-(-)-Ibuprofen
Catalog No.: PC-45990Not For Human Use, Lab Use Only.
An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.
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An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids; inhibits NF-κB activation (IC50=121.8 uM) in response to T-cell stimulation as well as block superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 =40-100 uM).
Pain
Approved
| M.Wt | 206.2808 | |
| Formula | C13H18O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
2. Evans AM. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.
3. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
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