Chemical Structure : (S)-( )-Ibuprofen
CAS No.: 51146-56-6
Catalog No.: PC-45989Not For Human Use, Lab Use Only.
An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.
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An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively).
M.Wt | 206.2808 | |
Formula | C13H18O2 | |
Appearance | Solid | |
Storage |
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Solubility |
H2O: 1 mg/mL (Need ultrasonic and warming); DMSO: < 0.1 mg/mL |
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Chemical Name/SMILES |
Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αS)- |
1. Evans AM, et al. Br J Clin Pharmacol. 1991 Feb;31(2):131-8.
2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
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