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(S)-( )-Ibuprofen

Chemical Structure : (S)-( )-Ibuprofen

CAS No.: 51146-56-6

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(S)-( )-Ibuprofen ((S)-Ibuprofen)

Catalog No.: PC-45989Not For Human Use, Lab Use Only.

An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.

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5 g $72 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively).

Physicochemical Properties

M.Wt 206.2808
Formula C13H18O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: 1 mg/mL (Need ultrasonic and warming); DMSO: < 0.1 mg/mL
Chemical Name/SMILES

Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αS)-

References

1. Evans AM, et al. Br J Clin Pharmacol. 1991 Feb;31(2):131-8.

2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.

3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.

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