Chemical Structure : 4-BBPB
Catalog No.: PC-61602Not For Human Use, Lab Use Only.
4-BBPB is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
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4-BBPB is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
4-BBPB attenuates activity of neuronal nitric oxide synthase (nNOS), blunts ischemia-induced nitric oxide production, and provides neuroprotection in stroke models.
M.Wt | 293.454 | |
Formula | C21H27N | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Takahashi H, et al. Stroke. 1995 Sep;26(9):1676-82.
2. Narita N, et al. Eur J Pharmacol. 1995 Oct 6;293(3):277-80.
3. Yang ZJ, et al. Exp Neurol. 2010 Jan;221(1):166-74.
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