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4-BBPB maleate

Chemical Structure : 4-BBPB maleate

CAS No.: 207572-62-1

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4-BBPB maleate (BBPB maleate)

Catalog No.: PC-61601Not For Human Use, Lab Use Only.

4-BBPB maleate is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

4-BBPB maleate is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
4-BBPB maleate attenuates activity of neuronal nitric oxide synthase (nNOS), blunts ischemia-induced nitric oxide production, and provides neuroprotection in stroke models.

Physicochemical Properties

M.Wt 409.526
Formula C25H31NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-phenyl-1-(4-phenylbutyl) piperidine maleate

References

1. Takahashi H, et al. Stroke. 1995 Sep;26(9):1676-82.

2. Narita N, et al. Eur J Pharmacol. 1995 Oct 6;293(3):277-80.

3. Yang ZJ, et al. Exp Neurol. 2010 Jan;221(1):166-74.

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