A2AR antagonist P625

Chemical Structure : A2AR antagonist P625

Catalog No.: PC-26045Not For Human Use, Lab Use Only.

A2AR antagonist P625 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 15.1 nM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

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Biological Activity

Physicochemical Properties

M.Wt	399.52
Formula	C19H25N7OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(furan-2-yl)-5-(4-(2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)thiazolo[5,4-d]pyrimidin-7-amine

References

1. M Morozzi, et al. Neuropharmacology. 2026 May 1:288:110857.

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A2AR antagonist P625

Biological Activity

Physicochemical Properties

References

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