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AN-2690

Chemical Structure : AN-2690

CAS No.: 174671-46-6

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AN-2690 (Tavaborole;AN2690;AN 2690)

Catalog No.: PC-42761Not For Human Use, Lab Use Only.

AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis.

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50 mg $78 In stock
100 mg $118 In stock
250 mg $188 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis.
AN-2690 inhibits T. rubrum, T. mentagrophytes, C. albicans, C. neoformans with MIC50s of 0.25-1ug/mL.

Physicochemical Properties

M.Wt 151.9307
Formula C7H6BFO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-

References

1. Baker SJ, et al. J Med Chem. 2006 Jul 27;49(15):4447-50.

2. Rock FL, et al. Science. 2007 Jun 22;316(5832):1759-61.

3. Sarkar J, et al. FEBS Lett. 2011 Oct 3;585(19):2986-91.

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