Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AS1938909
Catalog No.: PC-21454Not For Human Use, Lab Use Only.
AS1938909 is a potent, selective and competitive SHIP2 inhibitor with Ki value of 0.44 uM (human SHIP2), shows significant selectivity over other related phosphatases.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AS1938909 is a potent, selective and competitive SHIP2 inhibitor with Ki value of 0.44 uM (human SHIP2), shows significant selectivity over other related phosphatases.
AS1938909 shows weak activity against human SHIP1 with Ki and IC50 values of 12 and 21 μM respectively.
AS1938909 shows potent inhibitory activity against human and mouse SHIP2 in a concentration-dependent manner, with IC50 values of 0.57 and 0.18 μM, respectively.
AS1938909 (1 nM) increases Akt phosphorylation and glucose consumption in L6 myotubes.
AS1938909 increases glucose uptake and GLUT1 mRNA in L6 and C2C12 myotubes.
| M.Wt | 428.27 | |
| Formula | C19H13Cl2F2NO2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Akira Suwa, et al. Eur J Pharmacol. 2010 Sep 10;642(1-3):177-82.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
