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AU-1235

Chemical Structure : AU-1235

CAS No.: 1338780-86-1

AU-1235 (AU1235)

Catalog No.: PC-61751Not For Human Use, Lab Use Only.

AU-1235 is a novel, specific mycobacterial membrane protein large 3 (MmpL3) inhibitor with MIC of 0.1 ug/mL (0.3 uM) against Mtb H37Rv..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AU-1235 is a novel, specific mycobacterial membrane protein large 3 (MmpL3) inhibitor with MIC of 0.1 ug/mL (0.3 uM) against Mtb H37Rv.

Physicochemical Properties

M.Wt 324.347
Formula C17H19F3N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Tricyclo[3.3.1.13,7]dec-1-yl-N'-(2,3,4-trifluorophenyl)urea

References

1. Grzegorzewicz AE, et al. Nat Chem Biol. 2012 Feb 19;8(4):334-41.

2. Stanley SA, et al. ACS Chem Biol. 2012 Aug 17;7(8):1377-84.

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