BMS-986278 | LPA1 antagonist | Probechem Biochemicals

Chemical Structure : BMS-986278

CAS No.: 2170126-74-4

Catalog No.: PC-72349Not For Human Use, Lab Use Only.

BMS-986278 (BMS986278) is a potent, selective lysophosphatidic acid receptor 1 (LPA1) antagonist with human LPA1 Kb of 6.9 nM.

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Biological Activity

BMS-986278 (BMS986278) is a potent, selective lysophosphatidic acid receptor 1 (LPA1) antagonist with human LPA1 Kb of 6.9 nM.

M.Wt	445.52
Formula	C22H31N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclohexanecarboxylic acid, 3-[[2-methyl-6-[1-methyl-5-[[[(methylpropylamino)carbonyl]oxy]methyl]-1H-1,2,3-triazol-4-yl]-3-pyridinyl]oxy]-, (1S,3S)-

1. Cheng PTW, et al. J Med Chem. 2021 Nov 11;64(21):15549-15581.

2. Corte TJ, et al. BMJ Open Respir Res. 2021 Dec;8(1):e001026.