BMS135 | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS135

BMS135 (BMS-135)

Catalog No.: PC-49097Not For Human Use, Lab Use Only.

BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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Biological Activity

BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

Physicochemical Properties

M.Wt	407.510
Formula	C25H29NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)ethan-1-ol

References

1. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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BMS135 (BMS-135)

Biological Activity

Physicochemical Properties

References

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