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BMS135

Chemical Structure : BMS135

CAS No.: 1675202-86-4

BMS135 (BMS-135)

Catalog No.: PC-49097Not For Human Use, Lab Use Only.

BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

    Physicochemical Properties

    M.Wt 407.510
    Formula C25H29NO4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)ethan-1-ol

    References

    1. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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