Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-11β-HSD-BVT-2733
BVT-2733

Chemical Structure : BVT-2733

CAS No.: 376640-41-4

BVT-2733 (BVT2733;BVT 2733)

Catalog No.: PC-45406Not For Human Use, Lab Use Only.

BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.

Packing Price Stock Quantity
10 mg $118 In stock
25 mg $198 In stock
50 mg $328 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BVT-2733 (BVT2733) is a non-steroidal, isoform-selective inhibitor of mouse 11β-HSD1 with Ki of 1 uM.
BVT-2733 displays >20-fold selectivity over 11β-HSD2.
BVT-2733 lowers hepatic PEPCK and glucose-6-phosphatase mRNA, blood glucose and serum insulin concentrations in a hyperglycaemic and hyperinsulinaemic mouse model.

Physicochemical Properties

M.Wt 428.9566
Formula C17H21ClN4O3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzenesulfonamide, 3-chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]-

References

1. Alberts P, et al. Diabetologia. 2002 Nov;45(11):1528-32.

2. Alberts P, et al. Endocrinology. 2003 Nov;144(11):4755-62.

3. Wang L, et al. PLoS One. 2012;7(7):e40056.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: