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Baloxavir Marboxil

Chemical Structure : Baloxavir Marboxil

CAS No.: 1985606-14-1

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Baloxavir Marboxil (S-033188, Xofluza, RG 6152)

Catalog No.: PC-35416Not For Human Use, Lab Use Only.

Baloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Baloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.

Physicochemical Properties

M.Wt 571.552
Formula C27H23F2N3O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

({(12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methyl methyl carbonate

References

1. Omoto S, et al. Sci Rep. 2018 Jun 25;8(1):9633.

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