Chemical Structure : CA-4948
CAS No.: 1801344-14-8
Catalog No.: PC-50002Not For Human Use, Lab Use Only.
Emavusertib (CA-4948) is a potent, selective and orally active IRAK4 inhibitor with IC50 of 31.7 nM.
Packing | Price | Stock | Quantity |
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5 mg | $58 | In stock | |
10 mg | $88 | In stock | |
25 mg | $138 | In stock | |
50 mg | $228 | In stock | |
100 mg | $378 | In stock | |
250 mg | Get quote |
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M.Wt | 491.508 | |
Formula | C24H25N7O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[5-[(3R)-3-Hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide |
1. Robert Booher, et al. 1534 Combination of IRAK4 Inhibitor CA-4948 with BCL2 Inhibitor Venetoclax Induces Tumor Regression in an ABC-DLBCL Xenograft Model. Bldg A, Lvl 1, Hall A2 (Georgia World Congress Center).
2. Gummadi VR, et al. ACS Med Chem Lett. 2020 Oct 14;11(12):2374-2381.
3. Zhang S, et al. Front Immunol. 2021 Mar 9;12:637659.
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