Catalog No.: PC-26360Not For Human Use, Lab Use Only.
Tifeglipron (CT-996, RO7795081, RG6652) is a potent, selective and orally active glucagon-like peptide 1 receptor (GLP-1R) agonist with EC50 of 0.49 nM.
Tifeglipron (CT-996, RO7795081, RG6652) is a potent, selective and orally active glucagon-like peptide 1 receptor (GLP-1R) agonist with EC50 of 0.49 nM. CT-996 reduces the β-arrestin recruitment and GLP-1R internalization. CT-996 suppresses postprandial blood glucose following a mixed meal tolerance test (MMTT) in mice expressing the human GLP-1 receptor and enhances glucose stimulated insulin secretion (GSIS) during an intravenous glucose challenge in obese monkeys.
