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CYT-0851

Chemical Structure : CYT-0851

CAS No.: 2301085-04-9

CYT-0851 (Emzadirib, CYT0851)

Catalog No.: PC-22006Not For Human Use, Lab Use Only.

CYT-0851 (Emzadirib) is a potent, selective and oral inhibitor of RAD51-mediated DNA repair, inhibits homologous recombination (HR) leading to an accumulation of unrepaired DSBs and tumor cell death.

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Biological Activity

CYT-0851 (Emzadirib) is a potent, selective and oral inhibitor of RAD51-mediated DNA repair, inhibits homologous recombination (HR) leading to an accumulation of unrepaired DSBs and tumor cell death.

Physicochemical Properties

M.Wt 580.76
Formula C27H40N4O6S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

isopropyl (3-(N-(tert-butyl)sulfamoyl)-4-(2-((1r,4r)-4-((isopropoxycarbonyl)amino)cyclohexyl)thiazol-5-yl)phenyl)carbamate

References

1. Ryan C Lynch, et al. Journal of Clinical Oncology, 2021. Volume 39, Number 15_suppl.

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