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DNV3837

Chemical Structure : DNV3837

CAS No.: 790704-42-6

DNV3837 (Oxaquin, MCB-3681)

Catalog No.: PC-38364Not For Human Use, Lab Use Only.

MCB 3681 is a quinolonyl-oxazolidinone bactericidal antibiotic, has activity in vitro against Gram-positive bacteria. MCB3681 has a potent in vitro activity against C. difficile with MIC90 of 0.064 ug/ml.

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    Biological Activity

    DNV3837 (Oxaquin, MCB 3681) is a quinolonyl-oxazolidinone bactericidal antibiotic, has activity in vitro against Gram-positive bacteria.
    DNV3837 (Oxaquin, MCB 3681) has a potent in vitro activity against C. difficile with MIC90 of 0.064 ug/ml.

    Physicochemical Properties

    M.Wt 626.60
    Formula C31H32F2N4O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-[4-[[4-[(5S)-5-[(Acetylamino)methyl]-2-oxo-3-oxazolidinyl]-2-fluorophenoxy]methyl]-4-hydroxy-1-piperidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

    References

    1. Rashid MU, et al. Int J Antimicrob Agents. 2014 Aug;44(2):125-30.

    2. Rashid MU, et al. Anaerobe. 2014 Aug;28:216-9.

    3. Dalhoff A, et al. Clin Microbiol Infect. 2015 Aug;21(8):767.e1-4.

    4. Freeman J, et al. Antimicrob Agents Chemother. 2017 Feb 23;61(3):e02077-16.

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