Catalog No.: PC-35289Not For Human Use, Lab Use Only.
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF-κB, salicylic acid and docosahexaenoic acid (DHA).
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF-κB, salicylic acid and docosahexaenoic acid (DHA).
Edasalonexent (CAT-1004) significantly inhibits NF-κB p65-dependent inflammatory responses as well as downstream proinflammatory genes modulated by p65 in the golden retriever DMD model.
Edasalonexent (CAT-1004) is hydrolyzed by FAAH to release salicylic acid and DHA intracellularly and to suppress activated NF-κB.
