Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : FC162
Catalog No.: PC-21495Not For Human Use, Lab Use Only.
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
FC162 is a potent inhibitor of DYRK1A with IC50 of 11, 18, and 68 nM, against DYRK1A, CLK1, and GSK3, respectively.
FC162 (0-30 uM) dose-dependently inhibits Tau phosphorylation at Thr21 in SH-SY5Y cells expressing Tau.
FC162 reduces cyclin D3 phosphorylation and impairs the entry to quiescent state.
FC162 treatment phenocopies the effect of Dyrk1a genetic deletion in pre-B cells.
| M.Wt | 320.37 | |
| Formula | C17H12N4OS | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Corinne Fruit, et al. Pharmaceuticals (Basel). 2019 Dec 17;12(4):185.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
