FV-100 |CAS:956483-03-7 Probechem Biochemicals

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Chemical Structure : FV-100

FV-100 (Valnivudine;FV100;CF-1743)

Catalog No.: PC-63468Not For Human Use, Lab Use Only.

FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.

HSV Infection

Phase 3 Clinical

Physicochemical Properties

M.Wt	548.077
Formula	C28H38ClN3O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	((2R,3S,5R)-3-hydroxy-5-(2-oxo-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-3(2H)-yl)tetrahydrofuran-2-yl)methyl (S)-3-amino-4-methylpentanoate hydrochloride

References

1. McGuigan C, et al. J Antimicrob Chemother. 2007 Dec;60(6):1316-30.

2. Pentikis HS, et al. Antimicrob Agents Chemother. 2011 Jun;55(6):2847-54.

3. Migliore M. Antivir Chem Chemother. 2010 Jan 5;20(3):107-15.

4. Tyring SK, et al. J Med Virol. 2017 Jul;89(7):1255-1264.

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FV-100 (Valnivudine;FV100;CF-1743)

Biological Activity

Physicochemical Properties

References

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