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Chemical Structure : GSK-3117391
CAS No.: 1018673-42-1
Catalog No.: PC-63389Not For Human Use, Lab Use Only.
GSK-3117391 (ESM-HDAC391, CHR-5154) is an orally active, myeloid-targeted histone deacetylase (HDAC) inhibitor with IC50 of 55 nM in a HeLa cell nuclear extract fluorometric assay, potently inhibits Class I, Class IIb and Class IV members (HDAC 1/2/3/8, HDAC6/10, and HDAC 11, respectively), with Class IIa enzymes (HDAC4/5/7/9) unaffected.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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| M.Wt | 389.496 | |
| Formula | C21H31N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
cyclopentyl (S)-2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)amino)acetate |
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1. Rebecca C Furze, et al. Br J Clin Pharmacol. 2022 Jun 2. doi: 10.1111/bcp.15428.
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