Catalog No.: PC-26709Not For Human Use, Lab Use Only.
GSK-F1 is a potent, selective phosphatidylinositol 4-kinase type IIIα (PI4KA) inhibitor with pIC50 of 8.0, also directly binds to NSUN2 and promote its proteasomal degradation.
GSK-F1 is a potent, selective phosphatidylinositol 4-kinase type IIIα (PI4KA) inhibitor with pIC50 of 8.0, also directly binds to NSUN2 and promote its proteasomal degradation. GSK-F1shows selectivity over PI4KB, PI3KA, PI3KB, PI3KG and PI3KD. GSK-F1 activates the downstream TP53/RAD51 signaling axis and increasing NPC cell cytotoxicity and radiosensitivity.
