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IL4 inhibitor 52

Chemical Structure : IL4 inhibitor 52

CAS No.: 1332184-63-0

IL4 inhibitor 52

Catalog No.: PC-72481Not For Human Use, Lab Use Only.

IL4 inhibitor 52 is the first IL-4 small-molecule inhibitor (EC50=1.81 uM) with potency for the cytokine and disrupts type II IL-4 signaling in cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IL4 inhibitor 52 is the first IL-4 small-molecule inhibitor (EC50=1.81 uM) with potency for the cytokine and disrupts type II IL-4 signaling in cells.

Physicochemical Properties

M.Wt 321.311
Formula C18H12FN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-amino-4-(3,4- dihydroxyphenyl)-6-(4-fluorophenyl)nicotinonitrile

References

1. Sean P Quinnell, et al. ACS Chem Biol. 2020 Oct 16;15(10):2649-2654.

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