Chemical Structure : JNJ-75276617
CAS No.: 2654081-35-1
Catalog No.: PC-21973Not For Human Use, Lab Use Only.
JNJ-75276617 (Bleximenib) is a potent, selective and orally bioavailable protein-protein interaction inhibitor of the binding between menin and KMT2A, binds to the menin protein with IC50 of 0.1 nM (human menin) in FITC assays.
Packing | Price | Stock | Quantity |
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2 mg | $358 | In stock | |
5 mg | $548 | In stock | |
10 mg | $898 | In stock | |
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M.Wt | 599.80 | |
Formula | C32H50FN7O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-N-ethyl-5-fluoro-N-isopropyl-2-((5-(2-(6-((2-methoxyethyl)(methyl)amino)-2-methylhexan-3-yl)-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl)oxy)benzamide |
1. Patent WO2022237720, compound A.
2, Patent WO2021121327, compound 27.
3, Kwon MC, et al. Blood. 2024 Jun 21:blood.2023022480.
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