LH1753 | L-cystine crystallization inhibitor

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Chemical Structure : LH1753

LH1753 (LH 1753)

Catalog No.: PC-22695Not For Human Use, Lab Use Only.

LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model.

Physicochemical Properties

M.Wt	630.57
Formula	C22H40N6O2S2.4ClH
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,2'R)-3,3'-disulfanediylbis(2-amino-1-(1,8-diazaspiro[4.5]decan-8-yl)propan-1-one) hydrochloride

References

1. Hu L, et al. ACS Med Chem Lett. 2024 Jun 6;15(7):1026-1031.

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LH1753 (LH 1753)

Biological Activity

Physicochemical Properties

References

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