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LH1753

Chemical Structure : LH1753

CAS No.: 2650492-10-5

LH1753 (LH 1753)

Catalog No.: PC-22695Not For Human Use, Lab Use Only.

LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model.

Physicochemical Properties

M.Wt 630.57
Formula C22H40N6O2S2.4ClH
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,2'R)-3,3'-disulfanediylbis(2-amino-1-(1,8-diazaspiro[4.5]decan-8-yl)propan-1-one) hydrochloride

References

1. Hu L, et al. ACS Med Chem Lett. 2024 Jun 6;15(7):1026-1031.

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