LJ5242

Chemical Structure : LJ5242

Catalog No.: PC-24592Not For Human Use, Lab Use Only.

LJ5157 is a LJ4827 derivative and potent, selective inhibitor of mitotic kinase HASPIN with IC50 of 8.27 uM, exhibits strong anti-tumor effects in gemcitabine resistant pancreatic cancer cells.

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Biological Activity

LJ5157 is a LJ4827 derivative and potent, selective inhibitor of mitotic kinase HASPIN with IC50 of 8.27 uM, exhibits strong anti-tumor effects in gemcitabine resistant pancreatic cancer cells.

Physicochemical Properties

M.Wt	332.34
Formula	C12H12N8O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-amino-7-((2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxytetrahydrothiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

References

1. Shin YZ, et al. Biomed Pharmacother. 2025 May 15;188:118135.

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LJ5242

Biological Activity

Physicochemical Properties

References

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