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Chemical Structure : LY3502970
Catalog No.: PC-72211Not For Human Use, Lab Use Only.
LY3502970 (Orforglipron, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.
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LY3502970 (Orforglipron, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.
LY3502970 is a partial agonist, biased toward G protein activation over β-arrestin recruitment at the GLP-1R.
| M.Wt | 882.974 | |
| Formula | C48H48F2N10O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO (8.8 mg/mL) |
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1. Kawai T, et al. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29959-29967.
2. Cong Z, et al. Nat Commun. 2021 Jun 18;12(1):3763.
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