Chemical Structure : LY3502970
CAS No.: 2212020-52-3
Catalog No.: PC-72211Not For Human Use, Lab Use Only.
LY3502970 (Orforglipron, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | $398 | In stock | |
| 250 mg | Get quote |
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LY3502970 (Orforglipron, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.
LY3502970 is a partial agonist, biased toward G protein activation over β-arrestin recruitment at the GLP-1R.
| M.Wt | 882.974 | |
| Formula | C48H48F2N10O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO (8.8 mg/mL) |
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| Chemical Name/SMILES |
3-((1S,2S)-1-(5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-3-(3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carbonyl)-1H-indol-1-yl)-2-methylcyclopropyl)-1,2,4-oxadiazol-5(4H)-one |
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1. Kawai T, et al. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29959-29967.
2. Cong Z, et al. Nat Commun. 2021 Jun 18;12(1):3763.

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